Scientific literature watch

New weapons to fight a new enemy: a systematic review of drug combinations against the drug-resistant fungus Candida auris

Mycoses • 2021.03.27

Gharehbolagh S.A, Izadi A., Talebi M., et al.

Bacterial mechanisms, Epidemiology, Surveillance
International
Candida auris, Drug antagonism, Drug combinations, Drug synergism

First Report of an Extensively Drug-Resistant ST23 Klebsiella pneumoniae of Capsular Serotype K1 Co-Producing CTX-M-15, OXA-48 and ArmA in Spain

Antibiotics • 2021.02.04

Hernández M., López-Urrutia L., Abad D., et al.

Identification of Bacterial Drug-Resistant Cells by the Convolutional Neural Network in Transmission Electron Microscope Images

Front. Microbiol. • 2022.03.15

Hayashi-Nishino M., Aoki K., Kishimoto A., et al.

Bacterial mechanisms, Methods
International
Convolutional neural network, Enoxacin-resistant Escherichia coli cells, Quinolones, Transmission electron microscopy

Treatment of Highly Drug-Resistant Pulmonary Tuberculosis

NEJM • 2020.03.05

Conradie F., Diacon A.H., Ngubane N., Howell P., Everitt D., Crook A.M., Mendel C.M., Egizi E., Moreira J., Timm J., McHugh T.D., Wills G.H., Bateson A., Hunt R., Van Niekerk C., Li M., Olugbosi M., Spigelman M., Nix-TB Trial Team

Clinical trial
International
Bedaquiline, Clinical trial, Diarylquinolines, Drug therapy, Linezolid, Mycobacterium tuberulosis, Nitroimidazoles, Pretomanid

Rational design of a new antibiotic class for drug-resistant infections

Nature • 2021.09.15

Durand-Reville T.F., Miller A.A., O’Donnell J.P. et al.

Mycobacteriophage–antibiotic therapy promotes enhanced clearance of drug-resistant Mycobacterium abscessus

Disease Models & Mechanisms • 2021.09.16

Johansen M.D., Alcaraz M., Dedrick R.M., et al.

Bacterial mechanisms, New antibiotics and alternatives
International
CFTR, Cystic fibrosis, Mycobacterium abscessus, Pathogenesis, Phage therapy, Zebrafish

The Comparative Effectiveness of Ceftolozane/Tazobactam versus Aminoglycoside- or Polymyxin-Based Regimens in Multi-Drug-Resistant Pseudomonas aeruginosa Infections

Antibiotics • 2022.05.06

Caffrey A.R., Appaneal H.J., Liao J.X., et al.

New antibiotics and alternatives
International
Aminoglycosides, Ceftolozane-tazobactam, Comparative effectiveness, Polymyxins, Pseudomonas aeruginosa

Fluorescence-Based Detection of Natural Transformation in Drug-Resistant Acinetobacter baumannii.

J Bacteriol • 2018.09.10

Anne-Sophie Godeux , et al.,

Bacterial mechanisms

An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections

ACS Cent. Sci. • 2022.08.10

Parker E.N., Cain B.C., Hajian B., et al.

New antibiotics and alternatives
International
ESKAPE pathogens, FabI inhibitors, Fabimycin, Novel antibiotic classes

Losing the Battle but Winning the War: Can Defeated Antibacterials Form Alliances to Combat Drug-Resistant Pathogens?

Antibiotics • 2021.05.28

Oh S.; Chau R.; Nguyen A.T., et al.

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