{"id":23501,"date":"2022-04-25T14:16:25","date_gmt":"2022-04-25T13:16:25","guid":{"rendered":"https:\/\/ppr-antibioresistance.inserm.fr\/?p=23501"},"modified":"2022-04-25T14:16:30","modified_gmt":"2022-04-25T13:16:30","slug":"johnson-johnson-launches-next-satellite-center-for-global-health-discovery-at-holistic-drug-discovery-and-development-centre-university-of-cape-town-focused-on-antimicrobial-resistance","status":"publish","type":"post","link":"https:\/\/ppr-antibioresistance.inserm.fr\/fr\/informations-et-communications\/actualites\/johnson-johnson-launches-next-satellite-center-for-global-health-discovery-at-holistic-drug-discovery-and-development-centre-university-of-cape-town-focused-on-antimicrobial-resistance\/","title":{"rendered":"Johnson & Johnson Launches Next Satellite Center for Global Health Discovery at Holistic Drug Discovery and Development Centre, University of Cape Town, focused on Antimicrobial Resistance"},"content":{"rendered":"\n

Article published on J&J website<\/a> on April 25, 2022<\/p>\n\n\n\n

The new Center is focused on outpacing the rising threat of antimicrobial resistance (AMR) and builds on Johnson & Johnson\u2019s longstanding commitment to tackle this challenge. The Satellite Center in Cape Town is the second site to open in Johnson & Johnson\u2019s network of research collaborations aimed at addressing the world\u2019s most pressing health challenges. The collaboration between Johnson & Johnson and H3D will help to further expand and strengthen Africa\u2019s scientific capacity as a global hub for discovery research.<\/p>\n\n\n\n

Johnson & Johnson (the Company) today announced the launch of the J&J Satellite Center for Global Health Discovery (Satellite Center) at the Holistic Drug Discovery and Development (H3D) Centre, University of Cape Town, in Cape Town, South Africa. This marks the latest expansion of the J&J Centers for Global Health Discovery (J&J Centers), a global network of research collaborations between the Company and leading research institutions to accelerate translational and discovery research to address some of the world\u2019s most pressing global health challenges. The Satellite Center at H3D will work to drive new solutions to address the present and rising threat of antimicrobial resistance (AMR) with a specific focus on multidrug-resistant Gram-negative bacteria (MDR-GNB).<\/p>\n\n\n\n

The establishment of the J&J Centers is a critical step in the creation of a larger, global scientific network that will help stimulate local innovation and support researchers to drive and advance discovery research and development (R&D). Together, teams from the Janssen Pharmaceutical Companies of Johnson & Johnson and H3D will leverage their combined global, institutional and regional strengths to bolster the early-stage science, innovation and talent development needed to tackle AMR, a prevalent threat in Africa and around the world.<\/p>\n\n\n\n

\u201cInvesting to increase the capacity of the innovation ecosystem in Africa is critical to strengthening the R&D pipeline for entrenched and emerging global health challenges,\u201d said Ruxandra Draghia-Akli, M.D., Ph.D., Global Head, Global Public Health R&D at Janssen Research & Development, LLC<\/strong>. \u201cBy leveraging the unique strengths of H3D and the J&J Centers, we can cultivate the talent and capacity needed to drive innovation in the global fight against AMR.\u201d<\/p>\n\n\n\n

AMR has been named\u00a0one of the top ten<\/a>\u00a0global health threats by the World Health Organization (WHO) and has the power to transform easily treated diseases into deadly killers by rendering medicines and medical innovations ineffective. In 2019, more than\u00a05 million<\/a>\u00a0deaths were attributed to AMR, making it one of the leading causes of death worldwide. MDR Gram-negative bacteria are particularly concerning to public health because of their resistance to multiple antibiotics and the\u00a0limited<\/a>\u00a0availability of treatment options. Currently, all\u00a0three<\/a>\u00a0of the resistant bacteria described as critical priority level by the WHO are Gram-negative.<\/p>\n\n\n\n

\u201cAntibiotics have been the backbone of modern medicine for more than a century, but increasing resistance threatens to render them ineffective,\u201d said Anil Koul, Ph.D., Vice President of Discovery and Partnerships, Global Public Health R&D at Janssen Research & Development, LLC<\/strong>. \u201cOur innovation in new antibiotic drug discovery must outpace this rising threat, and the new Satellite Center will build on Johnson & Johnson\u2019s legacy in AMR and H3D\u2019s expertise to help deliver this ambition more quickly to people in need.\u201d<\/p>\n\n\n\n

The AMR challenge is particularly\u00a0acute<\/a>\u00a0in Africa as well as Asia, where the transmission of pneumonia, diarrheal diseases, tuberculosis (TB), malaria and sexually transmitted infections, coupled with limited data surveillance, has created an environment where significant resistance to antibiotics can develop. Furthermore, local researchers have long faced systemic barriers to accessing the support, resources and infrastructure as well as new technological platforms that are key to tackling significant health challenges like AMR.<\/p>\n\n\n\n

\u201cWe must come together to advance investment in African-led innovation to protect the health of both our communities and the world,\u201d said Kelly Chibale, Ph.D., Founder and Director of H3D<\/strong>. \u201cIt is critical that local researchers have the opportunity to investigate the challenges that impact their communities, without having to leave those communities. Being embedded in local communities, H3D is uniquely positioned to provide this opportunity. This collaboration will further foster the talent and provide the tools and opportunity needed to create innovative solutions in public health.\u201d<\/p>\n\n\n\n

About the J&J Centers for Global Health Discovery<\/strong>
Johnson & Johnson is joining forces with renowned institutions and leveraging their regional networks to bolster innovation and health equity in parallel through the establishment of the J&J Centers for Global Health Discovery. The Satellite Centers will provide long-term opportunities for mentorship of emerging talent in the discovery sciences to stimulate both local innovation and capacity.<\/p>\n\n\n\n

Johnson & Johnson\u00a0launched<\/a>\u00a0the first Satellite Center in July 2021 at the London School of Hygiene & Tropical Medicine (LSHTM), which is focused on developing cutting-edge science to build the next-generation of drug regimens needed to treat all forms of tuberculosis (TB). The disease remains one of the most significant challenges in global health, responsible for\u00a01.5 million deaths in 2020<\/a>\u00a0and accounting for\u00a0nearly one-third<\/a>\u00a0of all deaths from AMR.<\/p>\n\n\n\n

The risk of intense epidemics is\u00a0growing<\/a>\u00a0rapidly, with the probability of novel disease outbreaks likely to increase three-fold in the coming decades. Despite this, the last decade has seen a consistent\u00a0decline<\/a>\u00a0in funding for basic science. The J&J Centers are an important step in turning this tide and delivering innovations needed to address the diseases that disproportionately impact the world\u2019s poorest and most vulnerable people.<\/p>\n\n\n\n

Additional Satellite Centers will be launched in the future. <\/p>\n\n\n\n

To learn more, visit\u00a0jnj.com\/global-public-health\/discovery-centers<\/a>.<\/p>\n\n\n\n

Johnson & Johnson\u2019s Efforts to Outpace Antimicrobial Resistance<\/strong>
Research at the new Satellite Center will build on Johnson & Johnson\u2019s decades of work accelerating innovation \u2013 from the lab to the last mile of healthcare \u2013 to outpace the threat of AMR. As a founding member of the\u00a0AMR Action Fund<\/a>\u00a0and\u00a0AMR Industry Alliance<\/a>, Johnson & Johnson has committed to investing in and advancing critical science, as well as providing access to antibiotics and safeguarding their long-term effectiveness, to meet public health needs. As part of these efforts, the Janssen Pharmaceutical Companies of Johnson & Johnson are leading the pursuit for novel vaccines and therapeutics to tackle a range of drug-resistant infections, including drug-resistant TB and E. coli.<\/p>\n\n\n\n

To learn more, visit,\u00a0JNJ.com\/AMR<\/a>.<\/p>\n\n\n\n

A Deep and Enduring Commitment to Africa<\/strong><\/p>\n\n\n\n

Since Johnson & Johnson first opened its doors in South Africa 90 years ago, the Company has been committed to transforming the health of people living in the country and across the continent, helping lead the charge against some of the most significant health threats in the region, like\u00a0COVID-19<\/a>,\u00a0TB<\/a>,\u00a0HIV<\/a>\u00a0and\u00a0Ebola<\/a>.<\/p>\n\n\n\n

Critically, Johnson & Johnson has responded to the COVID-19 pandemic by expanding capacity in Africa. In March 2022, Janssen Pharmaceuticals, Inc. completed a\u00a0landmark agreement<\/a>\u00a0with Aspen Pharmacare in South Africa to transfer its fill-and-finish manufacturing technology, allowing the first COVID-19 vaccine to be manufactured and sold by an African company for people living in Africa. In addition to building manufacturing capacity, the Janssen Pharmaceutical Companies of Johnson & Johnson included sites in Africa for its COVID-19 vaccine clinical trials, supported a large-scale COVID-19 vaccine implementation study in South Africa and was the first major manufacturer to sign a\u00a0purchase agreement<\/a>\u00a0to supply its vaccine to African Union countries.<\/p>\n\n\n\n

###<\/p>\n\n\n\n

About Johnson & Johnson<\/strong>
At Johnson & Johnson, we believe good health is the foundation of vibrant lives, thriving communities and forward progress. That\u2019s why for more than 130 years, we have aimed to keep people well at every age and every stage of life. Today, as the world\u2019s largest and most broadly-based healthcare company, we are committed to using our reach and size for good. We strive to improve access and affordability, create healthier communities, and put a healthy mind, body and environment within reach of everyone, everywhere. We are blending our heart, science and ingenuity to profoundly change the trajectory of health for humanity. Learn more at\u00a0www.jnj.com<\/a>. Follow us at\u00a0@JNJNews<\/a>.<\/p>\n\n\n\n

About the Janssen Pharmaceutical Companies of Johnson & Johnson<\/strong>
At Janssen, we\u2019re creating a future where disease is a thing of the past. We\u2019re the Pharmaceutical Companies of Johnson & Johnson, working tirelessly to make that future a reality for patients everywhere by fighting sickness with science, improving access with ingenuity, and healing hopelessness with heart. We focus on areas of medicine where we can make the biggest difference: Cardiovascular & Metabolism, Immunology, Infectious Diseases & Vaccines, Neuroscience, Oncology, and Pulmonary Hypertension.<\/p>\n\n\n\n

Learn more at\u00a0www.janssen.c<\/a>o<\/a>m<\/a>. Follow us at\u00a0www.twitter.com\/JanssenUS<\/a>\u00a0and\u00a0www.twitter.com\/JanssenGlobal<\/a>. Janssen Research & Development, LLC and Janssen Biotech, Inc. are part of the Janssen Pharmaceutical Companies of Johnson & Johnson.<\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

Article published on J&J website on April 25, 2022 The new Center is focused on outpacing the rising threat of antimicrobial resistance (AMR) and builds on Johnson & Johnson\u2019s longstanding commitment to tackle this challenge. 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