AccueilEmplois & formationsPost-doctoral fellow with expertise in animal experimentation for developing respiratory antibacterial strategies, French/German “TARGET-THERAPY” consortium

Post-doctoral fellow with expertise in animal experimentation for developing respiratory antibacterial strategies, French/German “TARGET-THERAPY” consortium

Détails de l'offre

  • Type de poste: CDD
  • Secteur : Public
  • Localité : France 
  • Limite de candidature : 31/01/2022
  • Profil de poste:
    Recherche et innovation
  • Domaine(s) :
    Microbiologie et Immunologie, Vétérinaire et milieu animal

Description

ORGANISATION/COMPANY: INSERM DR Grand Ouest
RESEARCH FIELD: Biological sciences › Biology
Biological sciences › Laboratory animal science
RESEARCHER PROFILE: Recognised Researcher (R2)
APPLICATION DEADLINE: 31/01/2022 18:00 – Europe/Brussels
LOCATION: France › Brest
TYPE OF CONTRACT: Temporary
JOB STATUS: Full-time
HOURS PER WEEK: 38.5
OFFER STARTING DATE: 01/04/2022
REFERENCE NUMBER: ANR-20-AMRB-0009

Offer description

We are seeking a highly motivated and talented individual to join our research team as a Postdoctoral Fellow. The selected candidate will work with a multi-disciplinary team of researchers within the framework of a bilateral French/German environment (ANR funded project “TARGET-THERAPY”, 2021-2024, granted to Dr Tony Le Gall and Prof Holger Schönherr,

2nd French-German call for projects on antimicrobial resistance 2020 “One Health: AMR in environmental reservoirs and colonizing antibiotic resistant bacteria”). The candidate will apply his/her expertise to evaluate original polymer-based materials (developed in collaboration with other partners involved in the project) to eliminate respiratory bacterial (Pseudomonas aeruginosa) infection.

Beyond in vitro investigations, mouse models mimicking clinically-relevant conditions of host susceptibility to antibiotic-resistant bacteria will be used to assess the effectiveness of therapeutic systems. The outcome of infection and treatment will be determined overtime by analyzing bacterial clearance, inflammation, and immune response.

Environment

The applicant will work under the scientific supervision of Dr Tony Le Gall at INSERM UMR 1078. He/She will benefit from a dynamic and stimulating scientific environment in Brest (3 teams, >100 persons, multiple nationalities) within the “Gene Transfer and Combined Therapeutic Approaches” (GTCA) team (head: Prof Dr Tristan Montier).

We work since 2015 in close interaction with all the partners involved in the “TARGET-THERAPY” project, in Reims, FR (Prof. Gilles Lemercier, UMR CNRS 7312) and Siegen, DE (Prof. Dr. Holger Schönherr, Chemistry & Biology (Cμ), and Prof. Dr. Ulrich Jonas, Macromolecular chemistry). Besides working at its home institution in Brest, the researcher will also work for animal experimentations (implying the use of infected animal models) at the “Biomedical Defense Research Institute” (IRBA) in Brétigny-sur-Orge, FR.

The applicant will participate in the network events of the project. Visits in the laboratories of other partners involved are possible.

Hosting Institution and unit

Institution: INSERM

Unit: INSERM UMR 1078

Name: Genetic, Functional Genomic and Biotechnologies

Director: Emmanuelle GENIN

Composition: 3 Teams, > 100 peoples

Address: 22 avenue Camille Desmoulins 29200 Brest, France

Website: https://www.univ-brest.fr/umr1078/?languageId=1

Contract

Type: Temporary

Duration: 2 years

Salary: To be determined according to the INSERM pay grids

Envisaged Start Date: April 1st, 2022

Contact for further information: Dr LE GALL Tony, tel: +33 (0)298 018 103, email: tony.le-gall@inserm.fr

Eligibility criteria

Applicants are strongly encouraged to provide all relevant informations related to their past experience in animal experimentation.

Selection process

Applicants must send a CV, letter(s) of reference and a cover letter to: Dr LE GALL Tony

Contact for further information: LE GALL Tony, tel: +33 (0)298 018 103, email: tony.le-gall@inserm.fr

Deadline for application: January 31, 2021 18:00 (Europe/Brussels)

Required Research Experiences

RESEARCH FIELD: Biological sciences › Biology
YEARS OF RESEARCH EXPERIENCE: 1 – 4

Offer Requirements

REQUIRED EDUCATION LEVEL: Biological sciences: PhD or equivalent
REQUIRED LANGUAGES: ENGLISH: Good

Skills/Qualifications

Strong background in bacteriology (skills in respiratory infection model are ideal)

Training and skills in animal models (ideally in respiratory infections) and related experimentations (histology, anatomo-pathology)

Background in immunology is not mandatory but would be a plus

Specific Requirements

  • Track record of innovative research and scientific publications/patents
  • Excellent organizational, interpersonal and oral communication skills
  • Ability to be productive and successful in an intense work environment
  • Possibility to work in several places : Inserm U1078, Brest, FR (main location) and “Biomedical Defense Research Institute’, IRBA, Brétigny-sur-Orge, FR.

Where to send your application

COMPANY: INSERM DR Grand Ouest
ORGANISATION/COMPANY: INSERM DR Grand Ouest

DEPARTMENT: INSERM 1078
ORGANISATION TYPE: Public Research Institution
https://grand-ouest.inserm.fr/
E-MAIL: tony.le-gall@inserm.fr
COUNTRY: France
CITY: Nantes
STATE/PROVINCE: France
POSTAL CODE: 44021
STREET: 63 Quai Magellan
PHONE: +33 (0)298 018 103