PhD student in Transcriptional mechanisms of antibiotic resistance, Montpellier

• ORGANISATION/COMPANY: Universite de Montpellier
• RESEARCH FIELD: Biological sciences
• RESEARCHER PROFILE: First Stage Researcher (R1)
• APPLICATION DEADLINE: 30/10/2021 23:00 – Europe/Brussels
• LOCATION: France/Montpellier
• TYPE OF CONTRACT: temporary
• JOB STATUS: Full-time
• HOURS PER WEEK: 38
• OFFER STARTING DATE: 01/09/2021
• EU RESEARCH FRAMEWORK PROGRAMME: H2020

OFFER DESCRIPTION

Work environment:

Position is available in Konstantin Brodolin’s team at IRIM (Montpellier, France). IRIM, a research center dedicated to the basic research in the fields of bacteriology, virology, and immunology. IRIM is located in the CNRS – University campus which provides rich and dynamic scientific environment. K. Brodolin’s team explores molecular mechanisms of transcription regulation in the pathogenic bacteria by using biochemical, biophysical and structural approaches. Major research focus is on the interplay between RNA polymerase, transcription factors and antibiotics.

Main mission:

Explore a role of transcriptional regulators in resistance to the antibiotic fidaxomicin targeting bacterial RNA polymerase.

Activities:

Successful candidate will explore molecular mechanisms of antibiotic resistance and will participate in development of the novel antibacterial molecules. Methods to be used will include/in silico/drug design, RNA-seq, Chip-seq and/in vitro/enzymatic assays.

Eligibility criteria

Studying in a Ph.D molecular biology / biochemistry

Skills/Qualifications:

– Molecular biology

– Biochemistry

– Microbiology

Selection process

Please forward CV , master degree marks and contact details of two persons for references to:

Dr. Konstantin Brodolin: konstantin.brodolin@irim.cnrs.fr