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Scientific literature watch

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Structural and functional characterization of the intracellular filament-forming nitrite oxidoreductase multiprotein complex

Nature • 2021.07.15

Chicano T.M., Dietrich L., de Almeida N.M. et al.

Bacterial mechanisms
International
Cryoelectron microscopy, Cryoelectron tomography, Tubule architecture, X-ray crystallography

trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo

Nature • 2021.03.19

Aron Z.D., Mehrani A., Hoffer E.D. et al.

Bacterial mechanisms
International
Cryoelectron microscopy, N. gonorrhoeae, Ribosome, Trans-translation

Substrate-engaged type III secretion system structures reveal gating mechanism for unfolded protein translocation

Nature • 2021.03.09

Miletic S., Fahrenkamp D., Goessweiner-Mohr N. et al.

Bacterial mechanisms
International
Bacterial secretion, Cryoelectron microscopy, Injectisomes, Membrane proteins, Pathogens

Structure and efflux mechanism of the yeast pleiotropic drug resistance transporter Pdr5

Nature • 2021.09.06

Harris A., Wagner M., Du D., et al.

Bacterial mechanisms
International
Antifungal compounds, Cryoelectron microscopy, Efflux mechanism, Membrane proteins, Permeation and transport, Pleiotropic drug resistance

Structural basis for tuning activity and membrane specificity of bacterial cytolysins

Nature • 2020.11.16

Shah N.R., Voisin T.B., Parsons E.S. , et al.

Visualization of the mechanosensitive ion channel MscS under membrane tension

Nature • 2021.02.10

Zhang Y., Daday C., Gu RX. et al.

Bacterial mechanisms
International
Cryoelectron microscopy, Membrane biophysics, MscS

The antibiotic darobactin mimics a β-strand to inhibit outer membrane insertase

Nature • 2021.04.14

Kaur H., Jakob R.P., Marzinek J.K. et al.

Bacterial mechanisms
International
Cryoelectron microscopy, Darobactin, Membrane structure and assembly, X-ray crystallography

Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance

Nature • 2021.06.14

Koripella R.K., Deep A., Agrawal E.K. et al.

Bacterial mechanisms, New antibiotics and alternatives
International
Cryoelectron microscopy, Mitochondria, Mitoribosome, Ribosome

Self-association of MreC as a regulatory signal in bacterial cell wall elongation

Nature • 2021.05.20

Martins A., Contreras-Martel C., Janet-Maitre M. et al.

Structural basis for CSPG4 as a receptor for TcdB and a therapeutic target in Clostridioides difficile infection

Nature • 2021.06.18

Chen P., Zeng J., Liu Z. et al.

Bacterial mechanisms, New antibiotics and alternatives
International
Bacterial toxins, C. difficile, Cryoelectron microscopy, CSPG4-mimicking decoy, TcdB

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